Como é que se diz isto em Inglês (EUA)? Having mates is really going to change things and make a difference.

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First, I would say that it is not natural in American English to refer to a marriage partner/boyfriend/girlfriend/significant other/life partner/friend as a "mate", although this is not entirely incorrect. The word "mate" doesn't give much information on the status/type of relationship. So you could be misunderstood. Second, "mates" is plural; so, if you are talking about your marriage partner or girlfriend, you could be in a lot of trouble, ha ha! In American English, you might say: "Being married/having a girlfriend/having someone you love can change your life significantly. Is this the meaning you intended?